Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY4R | P50391 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29577662 | 0.97 | SIRT5 (0.53) | SIRT5MMP3CTSKSIRT2SIRT1 | |
| SCHEMBL5523268 | 0.97 | SIRT5 (0.53) | SIRT5MMP3CTSKSIRT2SIRT1 | |
| SCHEMBL29417414 | 0.97 | SIRT5 (0.53) | SIRT5MMP3CTSKSIRT2SIRT1 | |
| Hydrochloric Acid SCHEMBL29692733 | 0.96 | SIRT5 (0.52) | SIRT5MMP3CTSKSIRT2SIRT1 | |
| SCHEMBL29791005 | 0.96 | SIRT2 (0.48) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL29791057 | 0.96 | SIRT2 (0.48) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL13276502 | 0.94 | TDP1 (0.44) | SIRT5MMP3SIRT2SIRT1SIRT3 | |
| SCHEMBL6856707 | 0.94 | SIRT5 (0.49) | SIRT5MMP3CTSKSIRT2SIRT1 | |
| SCHEMBL31046106 | 0.94 | SIRT2 (0.49) | SIRT2SIRT1SIRT3 | |
| SCHEMBL31045758 | 0.94 | SIRT2 (0.49) | SIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024197174-A1 | PEPTIDE SUBSTRATES AND INHIBITORS OF CATHEPSIN B | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-09-26 | — | — | WO | disclosed |