Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 11/20 | 0.81 |
| ▸ | NPC1 | O15118 | 4/20 | 0.81 |
| ▸ | RAB9A | P51151 | 4/20 | 0.81 |
| ▸ | MAPT | P10636 | 3/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.81 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.81 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.81 |
| ▸ | IKBKB | O14920 | 1/20 | 0.81 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.81 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.81 |
| ▸ | PRKCG | P05129 | 1/20 | 0.81 |
| ▸ | CDK1 | P06493 | 1/20 | 0.81 |
| ▸ | LYN | P07948 | 1/20 | 0.81 |
| ▸ | KIT | P10721 | 1/20 | 0.81 |
| ▸ | PIM1 | P11309 | 1/20 | 0.81 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.81 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.81 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.81 |
| ▸ | CDK2 | P24941 | 1/20 | 0.81 |
| ▸ | MARK3 | P27448 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440486 | 0.90 | AURKA (1.00) | AURKANPC1RAB9AMAPTMAPK1 | |
| SCHEMBL4621303 | 0.81 | NPC1 (0.87) | AURKANPC1RAB9AMAPTMAPK1 | |
| SCHEMBL5384269 | 0.81 | AURKA (0.87) | AURKANPC1RAB9AMAPTMAPK1 | |
| SCHEMBL20771413 | 0.80 | ABL1 (0.53) | AURKANPC1RAB9AMAPTMAPK1 | |
| SCHEMBL4591751 | 0.78 | KMT2A (0.61) | NPC1RAB9AMAPTMAPK1PRKCD | |
| SCHEMBL29845262 | 0.78 | KMT2A (0.61) | NPC1RAB9AMAPTMAPK1PRKCD | |
| SCHEMBL7775625 | 0.78 | AURKA (0.77) | AURKANPC1RAB9AMAPTMAPK1 | |
| SCHEMBL7775628 | 0.78 | AURKA (0.77) | AURKANPC1RAB9AMAPTMAPK1 | |
| SCHEMBL1518621 | 0.77 | MAPK10 (0.67) | AURKANPC1RAB9AMAPTMAPK1 | |
| SCHEMBL20927073 | 0.77 | AURKA (0.73) | AURKANPC1RAB9AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260076973-A1 | Compounds and methods for treating diseases caused by SARS-CoV-2 and other coronaviruses | Viradem, Inc. (US) | 2026-03-19 | — | — | US | disclosed |
| WO-2024151953-A1 | COMPOUNDS AND METHODS FOR TREATING DISEASES CAUSED BY SARS-COV-2 AND OTHER CORONAVIRUSES | VIRADEM INC. (US) | 2024-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260076973-A1 | Compounds and methods for treating diseases caused by SARS-CoV-2 and other coronaviruses | ACE2, ACE, SARS1 | AURKA 1573/4885NPC1 550/4885RAB9A 2878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.