Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 9/20 | 0.60 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.60 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.60 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.60 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.60 |
| ▸ | SRC | P12931 | 3/20 | 0.60 |
| ▸ | KDR | P35968 | 3/20 | 0.60 |
| ▸ | ABL1 | P00519 | 3/20 | 0.60 |
| ▸ | PRKDC | P78527 | 2/20 | 0.60 |
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | HCK | P08631 | 1/20 | 0.60 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.60 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.60 |
| ▸ | RET | P07949 | 2/20 | 0.55 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.52 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.52 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.52 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30405455 | 1.00 | MTOR (0.60) | MTORPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL20553461 | 1.00 | MTOR (0.60) | MTORPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL7906422 | 0.88 | SRC (0.67) | MTORPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL23150471 | 0.88 | MTOR (0.58) | MTORPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL31046967 | 0.87 | TGFBR1 (0.71) | MTORPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL20552950 | 0.87 | TGFBR1 (0.71) | MTORPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL30405677 | 0.87 | TGFBR1 (0.71) | MTORPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL30405094 | 0.86 | SRC (0.58) | MTORPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL4820128 | 0.85 | SRC (0.62) | MTORPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL20553170 | 0.84 | TGFBR1 (0.72) | MTORPIK3CAPIK3CDPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118978535-A | C40-, C28-and C32-linked rapamycin analogues as mTOR inhibitors | 锐新医药公司 | 2024-11-19 | — | — | CN | disclosed |
| CN-118894869-A | C40-, C28-and C32-linked rapamycin analogues as mTOR inhibitors | 锐新医药公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-112771054-B | C40-, C28-and C32-linked rapamycin analogues as mTOR inhibitors | 锐新医药公司 | 2024-08-16 | — | — | CN | disclosed |