Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21523835 | 0.79 | ALDH1A1 (0.49) | TP53MAPTMAPK1HSD17B10CYP1A2 | |
| SCHEMBL160032 | 0.78 | TP53 (0.51) | TP53MAPTMAPK1NOTUMHSD17B10 | |
| SCHEMBL1087642 | 0.78 | MAPT (0.56) | TP53MAPTMAPK1NOTUMHSD17B10 | |
| SCHEMBL29021918 | 0.76 | MAPT (0.50) | TP53MAPTMAPK1NOTUMHSD17B10 | |
| SCHEMBL25176595 | 0.74 | HCAR2 (0.55) | TP53MAPTMAPK1NOTUMHSD17B10 | |
| SCHEMBL13197123 | 0.74 | ALDH1A1 (0.55) | TP53MAPTMAPK1CYP1A2CYP2C19 | |
| SCHEMBL29909974 | 0.74 | ALDH1A1 (0.50) | TP53MAPTMAPK1NOTUMHSD17B10 | |
| SCHEMBL18255998 | 0.73 | MRGPRX4 (0.52) | TP53MAPTMAPK1NOTUMHSD17B10 | |
| SCHEMBL18973243 | 0.73 | MRGPRX4 (0.52) | TP53MAPTMAPK1NOTUMHSD17B10 | |
| SCHEMBL15784497 | 0.73 | HSD17B10 (0.60) | TP53MAPTMAPK1NOTUMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024149378-A1 | QUINOLINONE COMPOUND AND NAPHTHYRIDINONE COMPOUND AND USE THEREOF | 上海超阳药业有限公司 | 2024-07-18 | — | — | WO | disclosed |