SCHEMBL31047341

SCHEMBL31047341

Cn1c(N2CCC(F)(F)CC2)nc2c(NC(=O)c3ccc(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)cccc21

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31047333 0.89 KIF18A (0.71) KIF18A
SCHEMBL31613813 0.85 KIF18A (0.67) KIF18A
SCHEMBL30842136 0.85 KIF18A (0.66) KIF18A
SCHEMBL31613828 0.84 KIF18A (0.61) KIF18A
SCHEMBL22964485 0.84 KIF18A (1.00) KIF18A
SCHEMBL31047339 0.84 KIF18A (0.51) KIF18A
SCHEMBL31613819 0.83 KIF18A (0.60) KIF18A
SCHEMBL31047355 0.83 KIF18A (0.62) KIF18A
SCHEMBL31613841 0.83 KIF18A (0.62) KIF18A
SCHEMBL31694776 0.83 KIF18A (0.62) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024149189-A1 AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF 浙江海正药业股份有限公司 2024-07-18 — — WO disclosed
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