SCHEMBL31613819

SCHEMBL31613819

CC1CCn2c1nc1c(NC(=O)c3ccc(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)cccc12

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30842194 0.96 KIF18A (0.59) KIF18A
SCHEMBL31613820 0.89 KIF18A (0.60) KIF18A
SCHEMBL31694750 0.88 KIF18A (0.62) KIF18A
SCHEMBL31613838 0.87 KIF18A (0.59) KIF18A
SCHEMBL31613840 0.86 KIF18A (0.61) KIF18A
SCHEMBL30842134 0.86 KIF18A (0.61) KIF18A
SCHEMBL31613844 0.86 KIF18A (0.61) KIF18A
SCHEMBL31694776 0.85 KIF18A (0.62) KIF18A
SCHEMBL31613841 0.85 KIF18A (0.62) KIF18A
SCHEMBL31613828 0.85 KIF18A (0.61) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4567032-A1 KIF18A INHIBITOR COMPOUND, AND PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD THEREFOR AND USE THEREOF Changchun Genescience Pharmaceutical Co., Ltd. (CN) 2025-06-11 — — EP disclosed
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