Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.37 |
| ▸ | RELA | Q04206 | 2/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31047363 | 0.77 | PDE10A (0.38) | METHCRTR1HCRTR2NPC1RAB9A | |
| SCHEMBL31047332 | 0.72 | ACACB (0.38) | MAPTSMN1; SMN2ALDH1A1HTR3AHRH4 | |
| SCHEMBL31047360 | 0.71 | HCAR2 (0.41) | HCAR2 | |
| SCHEMBL31047361 | 0.71 | HCAR2 (0.41) | HCAR2 | |
| SCHEMBL15228809 | 0.71 | EGFR (0.36) | HTTMEN1KMT2APDE10AKDM4E | |
| SCHEMBL23967086 | 0.69 | GRIN2D (0.49) | ALDH1A1NFKB1HTR3AMEN1KMT2A | |
| SCHEMBL2799754 | 0.67 | PDPK1 (0.38) | NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21638319 | 0.67 | NQO2 (0.43) | RAB9AMAPTALDH1A1GAAHPGD | |
| SCHEMBL27344458 | 0.66 | CYP11B1 (0.32) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL17316625 | 0.66 | GRIN2D (0.47) | NPC1RAB9AMAPTALDH1A1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024149189-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2024-07-18 | — | — | WO | disclosed |