Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.41 |
| ▸ | CKS1B | P61024 | 3/20 | 0.39 |
| ▸ | SKP1 | P63208 | 3/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FSHR | P23945 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31047361 | 1.00 | HCAR2 (0.41) | HCAR2CKS1BSKP1SKP2TSHR | |
| SCHEMBL31047337 | 0.92 | HCAR2 (0.41) | HCAR2CKS1BSKP1SKP2TSHR | |
| SCHEMBL31047359 | 0.80 | ACACB (0.42) | HCAR2CKS1BSKP1SKP2TSHR | |
| SCHEMBL31047354 | 0.72 | KIF18A (0.49) | — | |
| SCHEMBL31047362 | 0.71 | MET (0.41) | HCAR2 | |
| SCHEMBL31047351 | 0.69 | TSHR (0.37) | TSHRFSHRGSK3BDYRK1ARXFP1 | |
| SCHEMBL31047350 | 0.69 | TSHR (0.37) | TSHRFSHRGSK3BDYRK1ARXFP1 | |
| SCHEMBL31047340 | 0.69 | IDH1 (0.37) | TSHRFSHRGSK3BRXFP1BRD4 | |
| SCHEMBL29532149 | 0.68 | METAP1 (0.46) | RXFP1METAP1 | |
| SCHEMBL22556188 | 0.68 | TDP1 (0.61) | TSHRMETAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024149189-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2024-07-18 | — | — | WO | disclosed |