Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31047362 | 0.72 | MET (0.41) | HTR3AHRH4PDE10AGAAHPGD | |
| SCHEMBL15508940 | 0.71 | NR1H2 (0.39) | OPRM1OPRL1PDE10ATSHRALDH1A1 | |
| SCHEMBL31047359 | 0.70 | ACACB (0.42) | ACACBGAATSHRDYRK1A | |
| SCHEMBL16277295 | 0.66 | BACE1 (0.47) | BACE1GRM5KCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL31047329 | 0.66 | BACE1 (0.47) | BACE1GRM5KCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL16755315 | 0.66 | BACE1 (0.56) | BACE1GRM5KCNH2OPRM1PDE10A | |
| SCHEMBL31083305 | 0.63 | BACE1 (0.43) | BACE1GRM5KCNH2HPGDALDH1A1 | |
| SCHEMBL16755341 | 0.63 | NUDT1 (0.44) | BACE1GRM5KCNH2MAPTSMN1; SMN2 | |
| SCHEMBL31082814 | 0.63 | BACE1 (0.43) | BACE1GRM5KCNH2HPGDTSHR | |
| SCHEMBL24756308 | 0.62 | OPRM1 (0.38) | BACE1OPRM1OPRL1PDE10AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024149189-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2024-07-18 | — | — | WO | disclosed |