Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 8/20 | 0.39 |
| ▸ | CASP6 | P55212 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 3/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31047688 | 0.88 | NPC1 (0.52) | SERPINE1NPC1RAB9AKDM4EGAA | |
| SCHEMBL31047695 | 0.85 | PARP1 (0.49) | SERPINE1NPC1RAB9AMAPTPARP1 | |
| SCHEMBL31047669 | 0.81 | SERPINE1 (0.65) | SERPINE1KDM4EGAAMEN1KMT2A | |
| SCHEMBL31047685 | 0.79 | SERPINE1 (0.69) | SERPINE1KDM4EGAAMEN1KMT2A | |
| SCHEMBL31047672 | 0.78 | SERPINE1 (0.49) | SERPINE1NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL31047682 | 0.78 | SERPINE1 (0.51) | SERPINE1NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL31047681 | 0.77 | SERPINE1 (0.50) | SERPINE1KDM4EGAAMEN1KMT2A | |
| SCHEMBL31047686 | 0.76 | PDE9A (0.44) | SERPINE1KDM4EGAATNKSTNKS2 | |
| SCHEMBL31047696 | 0.75 | SERPINE1 (0.69) | SERPINE1NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL31047683 | 0.75 | TNKS (0.52) | SERPINE1KDM4EMEN1KMT2APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496146-A | Preparation method of isoindoline diketone compound | 五邑大学 | 2024-08-16 | — | — | CN | disclosed |