Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 4/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31047682 | 0.80 | SERPINE1 (0.51) | SIRT1SERPINE1CYP1A1CYP1B1TNKS | |
| SCHEMBL31047669 | 0.80 | SERPINE1 (0.65) | SERPINE1CYP1A1CYP1B1TNKSTNKS2 | |
| SCHEMBL31047681 | 0.79 | SERPINE1 (0.50) | SERPINE1CYP1A1CYP1B1TNKSTNKS2 | |
| SCHEMBL31047696 | 0.78 | SERPINE1 (0.69) | SERPINE1CYP1A1CYP1B1TNKSTNKS2 | |
| SCHEMBL31047695 | 0.78 | PARP1 (0.49) | PDE9ASIRT1SERPINE1TNKSTNKS2 | |
| SCHEMBL31047685 | 0.78 | SERPINE1 (0.69) | SERPINE1TNKSTNKS2KDM4EGAA | |
| SCHEMBL31047675 | 0.77 | SERPINE1 (0.49) | GSTP1SERPINE1CYP1A1CYP1B1TNKS | |
| SCHEMBL31047688 | 0.77 | NPC1 (0.52) | SIRT1SERPINE1TNKSTNKS2KDM4E | |
| SCHEMBL31047677 | 0.76 | SERPINE1 (0.44) | SERPINE1TNKSTNKS2KDM4EGAA | |
| SCHEMBL31047698 | 0.74 | TYMP (0.45) | SERPINE1TNKSTNKS2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496146-A | Preparation method of isoindoline diketone compound | 五邑大学 | 2024-08-16 | — | — | CN | disclosed |