Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 3/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31014306 | 0.83 | SERPINE1 (0.46) | SERPINE1PARP1PARP2IDO1TNKS | |
| SCHEMBL31047682 | 0.82 | SERPINE1 (0.51) | SERPINE1PARP1PARP2TNKSMEN1 | |
| SCHEMBL31047669 | 0.82 | SERPINE1 (0.65) | SERPINE1PARP1TNKSMEN1KMT2A | |
| SCHEMBL31047681 | 0.81 | SERPINE1 (0.50) | SERPINE1PARP1TNKSMEN1KMT2A | |
| SCHEMBL31047695 | 0.80 | PARP1 (0.49) | SERPINE1PARP1TNKSPDE9ATNKS2 | |
| SCHEMBL31047696 | 0.80 | SERPINE1 (0.69) | SERPINE1PARP1PARP2TNKSMEN1 | |
| SCHEMBL31047685 | 0.80 | SERPINE1 (0.69) | SERPINE1PARP1PARP2TNKSMEN1 | |
| SCHEMBL31047675 | 0.76 | SERPINE1 (0.49) | SERPINE1PARP1TNKSMEN1KMT2A | |
| SCHEMBL31047683 | 0.76 | TNKS (0.52) | SERPINE1PARP1TNKSMEN1KMT2A | |
| SCHEMBL31047686 | 0.74 | PDE9A (0.44) | SERPINE1TNKSPDE9ACYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496146-A | Preparation method of isoindoline diketone compound | 五邑大学 | 2024-08-16 | — | — | CN | disclosed |