Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 8/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31048028 | 0.88 | GPR119 (0.42) | JAK1GPR119DDB1CRBNJAK3 | |
| SCHEMBL25093887 | 0.80 | USP30 (0.43) | JAK1GPR119DDB1CRBNJAK3 | |
| SCHEMBL31048004 | 0.78 | PIM1 (0.41) | USP30SSTR4KMT2A | |
| SCHEMBL27203039 | 0.78 | PDE4B (0.41) | GPR119USP30SSTR4KMT2A | |
| SCHEMBL31048018 | 0.78 | PIM1 (0.41) | USP30SSTR4KMT2A | |
| SCHEMBL31048035 | 0.76 | SCN10A (0.33) | SSTR4 | |
| SCHEMBL22912731 | 0.74 | BACE1 (0.52) | KMT2A | |
| SCHEMBL30212537 | 0.74 | BACE1 (0.52) | KMT2A | |
| SCHEMBL27202748 | 0.74 | CNR2 (0.47) | JAK1GPR119JAK3KMT2ANAMPT | |
| SCHEMBL26123146 | 0.72 | GPR119 (0.44) | JAK1GPR119DDB1CRBNJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178125-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | 1CBIO, INC. (US) | 2024-08-29 | — | — | WO | disclosed |