Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 6/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | POLR1A | O95602 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31048018 | 1.00 | PIM1 (0.41) | PIM1PIM2USP30EHMT2BACE1 | |
| SCHEMBL31048007 | 0.88 | NR1H2 (0.44) | PIM1PIM2USP30EHMT2POLR1A | |
| SCHEMBL27203039 | 0.82 | PDE4B (0.41) | USP30KMT2ASSTR4 | |
| SCHEMBL29148532 | 0.80 | USP30 (0.48) | USP30ALDH1A1MAPTBTKNPC1 | |
| SCHEMBL30849217 | 0.80 | USP30 (0.48) | USP30ALDH1A1MAPTBTKNPC1 | |
| SCHEMBL29148533 | 0.80 | USP30 (0.48) | USP30ALDH1A1MAPTBTKNPC1 | |
| SCHEMBL25215675 | 0.79 | USP30 (0.49) | USP30ALDH1A1MAPTMEN1TSHR | |
| SCHEMBL31048002 | 0.78 | JAK1 (0.40) | USP30KMT2ASSTR4 | |
| SCHEMBL22912731 | 0.78 | BACE1 (0.52) | BACE1ALDH1A1MAPTMEN1TSHR | |
| SCHEMBL30212537 | 0.78 | BACE1 (0.52) | BACE1ALDH1A1MAPTMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178125-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | 1CBIO, INC. (US) | 2024-08-29 | — | — | WO | disclosed |