Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27203610 | 0.93 | GPR119 (0.53) | GPR119HRH3MEN1MAPTTSHR | |
| SCHEMBL31048020 | 0.88 | MEN1 (0.45) | GPR119MEN1MAPTTSHRKMT2A | |
| SCHEMBL27203571 | 0.83 | GPR119 (0.52) | GPR119HRH3MEN1MAPTTSHR | |
| SCHEMBL27203482 | 0.82 | GPR119 (0.46) | GPR119HRH3MEN1MAPTTSHR | |
| SCHEMBL18038733 | 0.82 | GPR119 (0.52) | GPR119MEN1MAPTTSHRKMT2A | |
| SCHEMBL25738320 | 0.81 | PARP1 (0.47) | GPR119MEN1MAPTTSHRKMT2A | |
| SCHEMBL14802410 | 0.79 | SMN1; SMN2 (0.60) | GPR119HRH3MEN1MAPTTSHR | |
| SCHEMBL21063452 | 0.79 | GPR119 (0.52) | GPR119HRH3MEN1MAPTTSHR | |
| SCHEMBL29913781 | 0.79 | SMN1; SMN2 (0.60) | GPR119HRH3MEN1MAPTTSHR | |
| SCHEMBL21413717 | 0.79 | GPR119 (0.50) | GPR119HRH3MEN1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178125-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | 1CBIO, INC. (US) | 2024-08-29 | — | — | WO | disclosed |