Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29220935 | 0.91 | GPR119 (0.56) | GPR119DDB1CRBNPDE4BUSP30 | |
| SCHEMBL1698741 | 0.88 | GPR119 (0.60) | GPR119DDB1CRBNPDE4BUSP30 | |
| SCHEMBL29220941 | 0.87 | USP30 (0.46) | GPR119DDB1CRBNPDE4BUSP30 | |
| Lithium Ion SCHEMBL21063388 | 0.85 | DDB1 (0.44) | GPR119DDB1CRBNPDE4BUSP30 | |
| SCHEMBL25093966 | 0.83 | GPR119 (0.50) | GPR119MAPK1USP30NR1H2HRH3 | |
| SCHEMBL30019202 | 0.83 | GPR119 (0.50) | GPR119MAPK1USP30NR1H2HRH3 | |
| SCHEMBL21381699 | 0.82 | PIK3CA (0.50) | GPR119DDB1CRBNPDE4BUSP30 | |
| SCHEMBL30567990 | 0.82 | PIK3CA (0.50) | GPR119DDB1CRBNPDE4BUSP30 | |
| SCHEMBL31639929 | 0.82 | DDB1 (0.47) | GPR119DDB1CRBNPDE4BNAMPT | |
| SCHEMBL20757383 | 0.81 | DDB1 (0.46) | GPR119DDB1CRBNPDE4BNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118612-A1 | TARGETING COMPOUNDS | ZAFGEN, INC. (US) | 2019-06-20 | — | — | WO | disclosed |
| WO-2019118612-A1 | TARGETING COMPOUNDS | ZAFGEN, INC. (US) | 2019-06-20 | — | — | WO | disclosed |