SCHEMBL310481

SCHEMBL310481

CC(c1c(O)c2ccccc2oc1=O)c1c(O)c2ccccc2oc1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
VKORC1 Q9BQB6 2/20 0.82
NQO1 P15559 7/20 0.69
TOP1 P11387 1/20 0.69
CYP2C9 P11712 6/20 0.68
CRHBP P24387 1/20 0.68
CASP7 P55210 1/20 0.68
CASP6 P55212 1/20 0.68
CRHR2 Q13324 1/20 0.68
HIF1A Q16665 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32659670 1.00 VKORC1 (0.82) VKORC1NQO1TOP1CYP2C9CRHBP
SCHEMBL7349603 0.91 VKORC1 (1.00) VKORC1NQO1TOP1CYP2C9CRHBP
SCHEMBL14078661 0.90 NQO1 (0.73) VKORC1NQO1TOP1CYP2C9CRHBP
SCHEMBL18126686 0.86 NQO1 (0.78) VKORC1NQO1TOP1CYP2C9CRHBP
SCHEMBL14172134 0.85 NQO1 (0.68) VKORC1NQO1TOP1CYP2C9CRHBP
SCHEMBL8868322 0.84 VKORC1 (0.69) VKORC1NQO1CYP2C9
SCHEMBL8469143 0.84 VKORC1 (0.78) VKORC1NQO1TOP1CYP2C9CRHBP
SCHEMBL14078663 0.84 CYP2C9 (0.72) VKORC1NQO1TOP1CYP2C9CRHBP
SCHEMBL28761758 0.84 VKORC1 (0.69) VKORC1NQO1TOP1CYP2C9CRHBP
SCHEMBL8042698 0.83 CYP2C9 (0.86) VKORC1NQO1TOP1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 566 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2021158573-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
WO-2021158575-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
WO-2021042001-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES Natural Extraction Systems, LLC (US) 2021-03-04 WO claimed
EP-2611466-A2 SHEAR CONTROLLED RELEASE FOR STENOTIC LESIONS AND THROMBOLYTIC THERAPIES President and Fellows of Harvard College (US) 2013-07-10 EP claimed
WO-2012074588-A2 SHEAR CONTROLLED RELEASE FOR STENOTIC LESIONS AND THROMBOLYTIC THERAPIES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2012-06-07 WO claimed
US-8034119-B2 Delivering an agent to a patient's body BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-10-11 US claimed
US-20050031577-A1 Therapeutic polyesters and polyamides RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2005-02-10 US claimed
US-20040127996-A1 Delivering an agent to a patient's body BOSTON SCIENTIFIC SCIMED, INC. 2004-07-01 US claimed
EP-1387649-A1 DELIVERING AN AGENT TO A PATIENT'S BODY SciMed Life Systems, Inc. (US) 2004-02-11 EP claimed
US-6685745-B2 Delivering an agent to a patient's body SCIMED LIFE SYSTEMS, INC. 2004-02-03 US claimed
EP-1309354-A2 THERAPEUTIC POLYESTERS AND POLYAMIDES Rutgers, The State University (US) 2003-05-14 EP claimed
US-20020173818-A1 Delivering an agent to a patient's body BOSTON SCIENTIFIC SCIMED, INC. 2002-11-21 US claimed
WO-2002091957-A1 DELIVERING AN AGENT TO A PATIENT'S BODY SCIMED LIFE SYSTEM, INC. (US) 2002-11-21 WO claimed
US-20020071822-A1 Therapeutic polyesters and polyamides POLYMERIX CORPORATION 2002-06-13 US claimed
WO-2002009768-A2 THERAPEUTIC POLYESTERS AND POLYAMIDES RUTGERS, THE STATE UNIVERSITY (US) 2002-02-07 WO claimed
US-4334020-A Method of producing L-glutamic acid by fermentation AJINOMOTO COMPANY INCORPORATED (JP) 1982-06-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB VKORC1 2181/4885NQO1 234/4885TOP1 3440/4885
US-20020071822-A1 Therapeutic polyesters and polyamides NPEPPS, PAICS, PUF60 VKORC1 4089/4885NQO1 3920/4885TOP1 790/4885
US-20050031577-A1 Therapeutic polyesters and polyamides NPEPPS, PAICS, PUF60 VKORC1 3900/4885NQO1 3832/4885TOP1 817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.