SCHEMBL31258706

SCHEMBL31258706

NNC(=O)c1ncc2c(C(=O)C(F)F)cc(SCc3ccccc3)cn12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
KDM6B O15054 1/20 0.34
KDM4A O75164 1/20 0.34
KDM4D Q6B0I6 1/20 0.34
HIF1AN Q9NWT6 1/20 0.34
KDM5B Q9UGL1 1/20 0.34
KDM2A Q9Y2K7 1/20 0.34
MCL1 Q07820 1/20 0.34
BCL2A1 Q16548 1/20 0.34
CXCR2 P25025 1/20 0.33
ALDH1A1 P00352 3/20 0.33
CYP2C9 P11712 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
PKM P14618 1/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31049474 0.85 CXCR2 (0.38) KMT2AMEN1CXCR2ALDH1A1SMN1; SMN2
SCHEMBL31258801 0.83 ALDH1A1 (0.38) KMT2AMEN1CXCR2ALDH1A1HTT
SCHEMBL31049390 0.78 CXCR2 (0.34) KMT2AMEN1KDM6BKDM4AKDM4D
SCHEMBL31258705 0.77 MEN1 (0.34) KMT2AMEN1KDM6BKDM4AKDM4D
SCHEMBL31049368 0.73 CXCR2 (0.35) KMT2AMEN1KDM6BKDM4AKDM4D
SCHEMBL30713264 0.72 CA12 (0.40) KMT2AMEN1KDM6BKDM4AKDM4D
SCHEMBL30713258 0.71 HTT (0.37) KMT2AMEN1MCL1BCL2A1CXCR2
Lithium Ion SCHEMBL31049392 0.71 PTGDR2 (0.35) KMT2AMEN1KDM6BKDM4AKDM4D
SCHEMBL30713202 0.69 KMT2A (0.43) KMT2AMEN1ALDH1A1SMN1; SMN2MAPT
SCHEMBL27389846 0.69 ALDH1A1 (0.32) ALDH1A1HTTNPC1RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4716532-A2 BICYCLIC HETEROARYL COMPOUNDS Quantx Biosciences US, Inc. (US) 2026-04-01 EP disclosed
WO-2024243304-A2 BICYCLIC HETEROARYL COMPOUNDS QUANTX BIOSCIENCES US, INC. (US) 2024-11-28 WO disclosed