Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | S100A4 | P26447 | 1/20 | 0.48 |
| ▸ | GCGR | P47871 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12348719 | 0.88 | TARBP2 (0.52) | NPC1RAB9ATARBP2HSD17B10SMN1; SMN2 | |
| SCHEMBL4705049 | 0.87 | ESR1 (0.53) | NPC1RAB9AHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL29858707 | 0.86 | TARBP2 (0.54) | NPC1RAB9ATARBP2HSD17B10SMN1; SMN2 | |
| SCHEMBL29858410 | 0.86 | NPC1 (0.48) | NPC1RAB9AHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL4704556 | 0.86 | RAB9A (0.56) | NPC1RAB9AHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL3100114 | 0.85 | TSHR (0.54) | NPC1RAB9ATARBP2HSD17B10SMN1; SMN2 | |
| SCHEMBL3914366 | 0.85 | NPC1 (0.70) | NPC1RAB9AHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL29859324 | 0.84 | TARBP2 (0.55) | NPC1RAB9ATARBP2HSD17B10SMN1; SMN2 | |
| SCHEMBL3075952 | 0.84 | NPC1 (0.50) | NPC1RAB9ATARBP2HSD17B10SMN1; SMN2 | |
| SCHEMBL27549550 | 0.83 | TNKS (0.48) | NPC1RAB9AHSD17B10SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160270-B | Synthesis method of 2,3, 5-trisubstituted furan derivative | 浙江大学 | 2024-01-16 | — | — | CN | disclosed |
| CN-115160270-A | Synthetic method of 2,3,5-trisubstituted furan derivative | 浙江大学 | 2022-10-11 | — | — | CN | disclosed |
| EP-2210876-B1 | HETEROCYCLIC COMPOUND AS GLUCAGON ANTAGONIST | TAKEDA PHARMACEUTICAL (JP) | 2015-05-20 | — | — | EP | disclosed |
| US-8309580-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-11-13 | — | — | US | disclosed |
| US-20100256156-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-07 | — | — | US | disclosed |
| EP-2210876-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-07-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256156-A1 | HETEROCYCLIC COMPOUND | GLP1R, GPR119, GCGR | NPC1 3994/4885RAB9A 3790/4885TARBP2 4836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.