Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2809293 | 0.85 | REN (0.67) | REN | |
| SCHEMBL3105679 | 0.85 | REN (0.38) | REN | |
| SCHEMBL10183572 | 0.84 | REN (0.56) | REN | |
| SCHEMBL2807527 | 0.83 | REN (0.67) | REN | |
| SCHEMBL13132595 | 0.83 | REN (0.64) | REN | |
| SCHEMBL90734 | 0.82 | REN (0.60) | REN | |
| SCHEMBL8235903 | 0.82 | REN (0.60) | REN | |
| SCHEMBL89178 | 0.82 | REN (0.60) | REN | |
| SCHEMBL90372 | 0.82 | REN (0.54) | REN | |
| SCHEMBL4507373 | 0.82 | REN (0.58) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249163-A1 | RENIN INHIBITORS | MERCK CANADA INC. (CA) | 2010-09-30 | — | — | US | disclosed |
| US-20100249163-A1 | RENIN INHIBITORS | MERCK CANADA INC. (CA) | 2010-09-30 | — | — | US | disclosed |
| US-20100249163-A1 | RENIN INHIBITORS | MERCK CANADA INC. (CA) | 2010-09-30 | — | — | US | disclosed |
| EP-2229363-A1 | RENIN INHIBITORS | Merck Frosst Canada Ltd. (CA) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009070869-A1 | RENIN INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2009-06-11 | — | — | WO | disclosed |
| WO-2009070869-A1 | RENIN INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2009-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249163-A1 | RENIN INHIBITORS | REN, ACE, AGTR1 | REN 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.