Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16695820 | 0.85 | ADORA3 (0.61) | ADORA3PARP1ALDH1A1KDM4EHPGD | |
| SCHEMBL16695706 | 0.78 | PARP1 (0.68) | PARP1ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL31330209 | 0.78 | ADORA3 (0.53) | ADORA3PARP1ALDH1A1KDM4EHPGD | |
| SCHEMBL30924898 | 0.78 | ADORA3 (0.43) | ADORA3KDM5AKDM5BALDH1A1KDM4E | |
| SCHEMBL30924896 | 0.76 | KDM4E (0.76) | KDM5AKDM5BALDH1A1KDM4EHPGD | |
| SCHEMBL12756114 | 0.76 | KDM4E (0.76) | KDM5AKDM5BALDH1A1KDM4EHPGD | |
| SCHEMBL27267212 | 0.76 | KDM4E (0.50) | ADORA3KDM5AKDM5BALDH1A1KDM4E | |
| SCHEMBL31410803 | 0.76 | ADORA3 (0.74) | ADORA3KDM5AKDM5BALDH1A1KDM4E | |
| SCHEMBL11060384 | 0.74 | ADORA3 (0.62) | ADORA3ALDH1A1KDM4ERAB9AGABRP | |
| SCHEMBL24760670 | 0.72 | KDM4E (0.44) | ADORA3ALDH1A1KDM4EHPGDGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12071437-B1 | Pyrazolo[1,5-a]pyrido[4,3-e]pyrimidine-2-carboxylic acids as CK2 inhibitors | King Faisal University (SA) | 2024-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12071437-B1 | Pyrazolo[1,5-a]pyrido[4,3-e]pyrimidine-2-carboxylic acids as CK2 inhibitors | CDK2, PDXK, SKP2 | ADORA3 861/4885KDM5A 2540/4885KDM5B 2978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.