Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 4/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31052827 | 0.84 | GRN (0.47) | GRNSORT1HCAR3ITGB1ITGA4 | |
| SCHEMBL31052861 | 0.81 | GRN (0.42) | GRNSORT1ALDH1A1 | |
| SCHEMBL31052825 | 0.80 | SORT1 (0.44) | GRNSORT1PYGLCYP2C9ITGB1 | |
| SCHEMBL31052826 | 0.80 | GRN (0.41) | GRNSORT1PYGLCYP2C9ITGB1 | |
| SCHEMBL31052821 | 0.77 | GRN (0.44) | GRNSORT1PYGLCYP2C9ITGB1 | |
| SCHEMBL31052857 | 0.76 | PSMB5 (0.39) | GRNSORT1ALDH1A1 | |
| SCHEMBL31052764 | 0.76 | KDM4E (0.48) | GRNSORT1PYGLCYP2C9ALDH1A1 | |
| SCHEMBL31052820 | 0.75 | GRN (0.45) | GRNSORT1PYGLCYP2C9HCAR2 | |
| SCHEMBL31052773 | 0.75 | GRN (0.46) | GRNSORT1ALDH1A1 | |
| SCHEMBL31052801 | 0.74 | GRN (0.46) | GRNSORT1PYGLCYP2C9RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676914-A1 | MODULATORS OF SORTILIN ACTIVITY | Vesper Bio Aps (DK) | 2026-01-14 | — | — | EP | claimed |
| WO-2024184469-A1 | MODULATORS OF SORTILIN ACTIVITY | VESPER BIO APS (DK) | 2024-09-12 | — | — | WO | claimed |
| EP-4428121-A1 | MODULATORS OF SORTILIN ACTIVITY | Vesper Bio Aps (DK) | 2024-09-11 | — | — | EP | claimed |
| EP-4676914-A1 | MODULATORS OF SORTILIN ACTIVITY | Vesper Bio Aps (DK) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024184469-A1 | MODULATORS OF SORTILIN ACTIVITY | VESPER BIO APS (DK) | 2024-09-12 | — | — | WO | disclosed |
| EP-4428121-A1 | MODULATORS OF SORTILIN ACTIVITY | Vesper Bio Aps (DK) | 2024-09-11 | — | — | EP | disclosed |