Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 5/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 5/20 | 0.45 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31052905 | 0.94 | GRN (0.41) | GRNSORT1BCAT2PYGLCYP2C9 | |
| SCHEMBL31052770 | 0.83 | FDPS (0.44) | GRNSORT1CYP2C9ALDH1A1 | |
| SCHEMBL31052871 | 0.82 | GRN (0.45) | GRNSORT1RIPK1HPGDMAPK1 | |
| SCHEMBL29213384 | 0.81 | GRN (0.42) | GRNSORT1PYGLCYP2C9ITGAV | |
| SCHEMBL29213463 | 0.81 | GRN (0.42) | GRNSORT1PYGLCYP2C9ITGAV | |
| SCHEMBL29213385 | 0.81 | GRN (0.42) | GRNSORT1PYGLCYP2C9ITGAV | |
| SCHEMBL29213382 | 0.81 | GRN (0.42) | GRNSORT1PYGLCYP2C9ITGAV | |
| SCHEMBL31052824 | 0.80 | GRN (0.48) | GRNSORT1PYGLCYP2C9RIPK1 | |
| SCHEMBL29213336 | 0.79 | GRN (0.43) | GRNSORT1PYGLCYP2C9ITGAV | |
| SCHEMBL29213329 | 0.79 | GRN (0.43) | GRNSORT1PYGLCYP2C9ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676914-A1 | MODULATORS OF SORTILIN ACTIVITY | Vesper Bio Aps (DK) | 2026-01-14 | — | — | EP | claimed |
| WO-2024184469-A1 | MODULATORS OF SORTILIN ACTIVITY | VESPER BIO APS (DK) | 2024-09-12 | — | — | WO | claimed |
| EP-4428121-A1 | MODULATORS OF SORTILIN ACTIVITY | Vesper Bio Aps (DK) | 2024-09-11 | — | — | EP | claimed |
| EP-4676914-A1 | MODULATORS OF SORTILIN ACTIVITY | Vesper Bio Aps (DK) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024184469-A1 | MODULATORS OF SORTILIN ACTIVITY | VESPER BIO APS (DK) | 2024-09-12 | — | — | WO | disclosed |
| EP-4428121-A1 | MODULATORS OF SORTILIN ACTIVITY | Vesper Bio Aps (DK) | 2024-09-11 | — | — | EP | disclosed |