Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3111171 | 0.85 | TYMP (0.37) | PDK2TYMPCYP1A2CYP2C9TSHR | |
| SCHEMBL3112403 | 0.81 | — | — | |
| SCHEMBL4751334 | 0.80 | PDK2 (0.45) | PDK2PDK4TYMP | |
| SCHEMBL4152719 | 0.74 | KDM4E (0.33) | — | |
| SCHEMBL2823399 | 0.72 | KDM4E (0.43) | PDK2PDK4TYMPCYP2C9HSD17B10 | |
| SCHEMBL7572064 | 0.70 | PDK2 (0.36) | PDK2PDK4GLA | |
| SCHEMBL6123017 | 0.68 | TYMP (0.38) | PDK2PDK4TYMPCYP1A2CYP2C9 | |
| SCHEMBL606 | 0.67 | PDK2 (0.37) | PDK2PDK4GLA | |
| SCHEMBL27987556 | 0.65 | SMPD3 (0.38) | — | |
| SCHEMBL9156390 | 0.64 | GLA (0.39) | PDK2PDK4TYMPCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141151-B1 | METHOD FOR PRODUCING 2-HALOIMIDAZOLE COMPOUND | SHIKOKU CHEM (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-2141151-A1 | METHOD FOR PRODUCING 2-HALOIMIDAZOLE COMPOUND | SHIKOKU CHEMICALS CORPORATION (JP) | 2010-01-06 | — | — | EP | disclosed |