SCHEMBL6123017

SCHEMBL6123017

CCCCc1[nH]c(Cl)nc1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMP P19971 4/20 0.38
PDK2 Q15119 2/20 0.36
PDK4 Q16654 1/20 0.36
CCNB2 O95067 1/20 0.35
CDK1 P06493 1/20 0.35
CCNB1 P14635 1/20 0.35
GSK3A P49840 1/20 0.35
GSK3B P49841 1/20 0.35
CCNB3 Q8WWL7 1/20 0.35
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 3/20 0.33
MAPK1 P28482 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
TSHR P16473 1/20 0.32
CYP2C19 P33261 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
HCAR2 Q8TDS4 2/20 0.31
TLR8 Q9NR97 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4751334 0.88 PDK2 (0.45) TYMPPDK2PDK4
SCHEMBL28040678 0.79 ALDH1A1 (0.37) TYMPPDK2PDK4KDM4EALDH1A1
SCHEMBL3111171 0.76 TYMP (0.37) TYMPPDK2ALDH1A1CYP1A2CYP2C9
SCHEMBL28831410 0.76 ALDH1A1 (0.37) KDM4EALDH1A1MAPK1L3MBTL1
SCHEMBL31087180 0.76 KDM4E (0.55) TYMPKDM4EALDH1A1TSHRHSD17B10
SCHEMBL3096722 0.74 TYMP (0.39) TYMPALDH1A1
SCHEMBL28138958 0.72 ALDH1A1 (0.39) TYMPALDH1A1
SCHEMBL28052800 0.72 ALDH1A1 (0.39) TYMPALDH1A1
SCHEMBL28139630 0.72 ALDH1A1 (0.39) TYMPALDH1A1
Bromide SCHEMBL28139631 0.71 ALDH1A1 (0.38) TYMPALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117105742-A Method for preparing high added value chlorohydrin by capturing HCl and catalyzing reaction with epoxide by using imidazole-based eutectic solvent 南京大学 2023-11-24 CN disclosed
CN-114432840-A Desulfurizing agent for carbon-containing and hydrogen sulfide gas, desulfurizing method and desulfurizing system 中国石油化工股份有限公司 2022-05-06 CN disclosed
US-20120283500-A1 METHODS FOR REGENERATING AND MAINTAINING ACTIVITY OF IONIC LIQUID CATALYST AND PRODUCING ALKYLATE CHINA UNIVERSITY OF PETROLEUM (BEIJING) (CN) 2012-11-08 US disclosed
EP-2455358-A1 METHODS FOR REGENERATING AND MAINTAINING ACTIVITY OF IONIC LIQUID CATALYST AND PRODUCING ALKYLATE Shell Internationale Research Maatschappij B.V. (NL) 2012-05-23 EP disclosed