Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3096722 | 0.98 | TYMP (0.39) | TYMPALDH1A1PKMHPGDKCNH2 | |
| SCHEMBL3105280 | 0.85 | PDK2 (0.44) | TYMPCYP1A2CYP2C9TSHRCYP2C19 | |
| SCHEMBL4152719 | 0.78 | KDM4E (0.33) | — | |
| SCHEMBL3112403 | 0.76 | — | — | |
| SCHEMBL6123017 | 0.76 | TYMP (0.38) | TYMPALDH1A1CYP1A2CYP2C9TSHR | |
| SCHEMBL129 | 0.69 | GPR84 (0.45) | TYMPALDH1A1PKMHPGDGPR84 | |
| SCHEMBL9081842 | 0.69 | GPR84 (0.45) | TYMPALDH1A1PKMHPGDGPR84 | |
| SCHEMBL8790906 | 0.65 | ALDH1A1 (0.42) | ALDH1A1CYP1A2CYP2C9TSHRCYP2C19 | |
| SCHEMBL3103281 | 0.65 | TYMP (0.39) | TYMPALDH1A1CYP1A2CYP2C9TSHR | |
| SCHEMBL24943560 | 0.65 | ALDH1A1 (0.38) | ALDH1A1CYP1A2CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141151-B1 | METHOD FOR PRODUCING 2-HALOIMIDAZOLE COMPOUND | SHIKOKU CHEM (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-2141151-A1 | METHOD FOR PRODUCING 2-HALOIMIDAZOLE COMPOUND | SHIKOKU CHEMICALS CORPORATION (JP) | 2010-01-06 | — | — | EP | disclosed |