Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 7/20 | 0.40 |
| ▸ | GRN | P28799 | 3/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.36 |
| ▸ | ITGAV | P06756 | 3/20 | 0.35 |
| ▸ | ITGB6 | P18564 | 3/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31052846 | 0.84 | PTGDR (0.41) | SORT1GRNPYGLCYP2C9ITGAV | |
| SCHEMBL31052821 | 0.80 | GRN (0.44) | SORT1GRNPYGLCYP2C9ITGB1 | |
| SCHEMBL31052893 | 0.80 | ITGAV (0.44) | SORT1GRNPYGLCYP2C9ITGAV | |
| SCHEMBL31052773 | 0.78 | GRN (0.46) | SORT1GRN | |
| SCHEMBL31052797 | 0.76 | ITGAV (0.42) | SORT1GRNITGAVITGB6ITGB1 | |
| SCHEMBL31052861 | 0.76 | GRN (0.42) | SORT1GRN | |
| SCHEMBL31052763 | 0.76 | GRN (0.42) | SORT1GRNPYGLCYP2C9ITGB1 | |
| SCHEMBL31052825 | 0.75 | SORT1 (0.44) | SORT1GRNPYGLCYP2C9ITGAV | |
| SCHEMBL31052801 | 0.75 | GRN (0.46) | SORT1GRNPYGLCYP2C9RIPK1 | |
| SCHEMBL31052914 | 0.74 | GRN (0.43) | SORT1GRNPYGLCYP2C9ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676914-A1 | MODULATORS OF SORTILIN ACTIVITY | Vesper Bio Aps (DK) | 2026-01-14 | — | — | EP | claimed |
| WO-2024184469-A1 | MODULATORS OF SORTILIN ACTIVITY | VESPER BIO APS (DK) | 2024-09-12 | — | — | WO | claimed |
| EP-4428121-A1 | MODULATORS OF SORTILIN ACTIVITY | Vesper Bio Aps (DK) | 2024-09-11 | — | — | EP | claimed |
| EP-4676914-A1 | MODULATORS OF SORTILIN ACTIVITY | Vesper Bio Aps (DK) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024184469-A1 | MODULATORS OF SORTILIN ACTIVITY | VESPER BIO APS (DK) | 2024-09-12 | — | — | WO | disclosed |
| EP-4428121-A1 | MODULATORS OF SORTILIN ACTIVITY | Vesper Bio Aps (DK) | 2024-09-11 | — | — | EP | disclosed |