Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 19/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22848180 | 0.93 | KRAS (0.38) | KRAS | |
| SCHEMBL31052998 | 0.86 | KRAS (0.46) | KRAS | |
| SCHEMBL28696808 | 0.83 | KRAS (0.41) | KRAS | |
| SCHEMBL22848023 | 0.79 | KRAS (0.36) | KRAS | |
| SCHEMBL31053002 | 0.79 | KRAS (0.36) | KRAS | |
| SCHEMBL22848276 | 0.78 | KRAS (0.51) | KRAS | |
| SCHEMBL31053009 | 0.78 | KRAS (0.36) | KRAS | |
| SCHEMBL31053006 | 0.77 | KRAS (0.32) | KRAS | |
| SCHEMBL22724637 | 0.73 | KRAS (0.49) | KRAS | |
| SCHEMBL30957847 | 0.73 | KRAS (0.49) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008037-B | Heterocyclic compounds as KRAS G12C inhibitors | 广东新契生物医药科技有限公司 | 2024-06-21 | — | — | CN | disclosed |