Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29238689 | 0.86 | GSTP1 (0.38) | MEN1ALDH1A1RAB9AKMT2AGSTP1 | |
| SCHEMBL22848181 | 0.84 | GSTP1 (0.40) | MEN1ALDH1A1RAB9AKMT2AGSTP1 | |
| SCHEMBL31053010 | 0.66 | KRAS (0.35) | — | |
| SCHEMBL24660012 | 0.65 | CCNC (0.42) | ALDH1A1KMT2A | |
| SCHEMBL21852192 | 0.65 | GSTP1 (0.42) | MEN1ALDH1A1RAB9AKMT2AGSTP1 | |
| SCHEMBL21855915 | 0.64 | CXCR1 (0.42) | MEN1ALDH1A1RAB9AKMT2AGSTP1 | |
| SCHEMBL18320494 | 0.64 | KMT2A (0.43) | MEN1ALDH1A1RAB9AKMT2AGSTP1 | |
| SCHEMBL30660933 | 0.64 | KMT2A (0.43) | MEN1ALDH1A1RAB9AKMT2AGSTP1 | |
| SCHEMBL29506185 | 0.64 | CXCR1 (0.42) | MEN1ALDH1A1RAB9AKMT2AGSTP1 | |
| SCHEMBL22848251 | 0.64 | CCNB2 (0.39) | MEN1ALDH1A1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008037-B | Heterocyclic compounds as KRAS G12C inhibitors | 广东新契生物医药科技有限公司 | 2024-06-21 | — | — | CN | disclosed |