SCHEMBL31053017

SCHEMBL31053017

N#Cc1ccc(Cl)c(O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
HSD17B10 Q99714 2/20 0.50
ALDH1A1 P00352 1/20 0.50
CYP3A4 P08684 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
VCAM1 P19320 1/20 0.48
CA12 O43570 1/20 0.46
CA2 P00918 1/20 0.46
CA3 P07451 1/20 0.46
CA6 P23280 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CYP19A1 P11511 1/20 0.46
AR P10275 3/20 0.42
MMP3 P08254 1/20 0.41
CXCR2 P25025 3/20 0.40
CXCR1 P25024 2/20 0.40
TMPRSS4 Q9NRS4 1/20 0.39
PDGFRB P09619 1/20 0.39
KDR P35968 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3759580 1.00 TSHR (0.50) TSHRHSD17B10ALDH1A1CYP3A4TDP1
SCHEMBL407449 0.82 TSHR (0.50) TSHRHSD17B10VCAM1CA12CA2
SCHEMBL217250 0.78 CA12 (0.52) TSHRHSD17B10ALDH1A1CYP3A4CA12
SCHEMBL29449995 0.78 CA12 (0.52) TSHRHSD17B10ALDH1A1CYP3A4CA12
SCHEMBL825866 0.78 VCAM1 (0.53) TSHRHSD17B10ALDH1A1CYP3A4VCAM1
SCHEMBL11092340 0.77 HSD17B10 (0.50) TSHRHSD17B10ALDH1A1CYP3A4TDP1
SCHEMBL23271632 0.76 CA12 (0.50) TSHRHSD17B10ALDH1A1CYP3A4CA12
SCHEMBL28759539 0.76 CA12 (0.50) TSHRHSD17B10ALDH1A1CYP3A4CA12
Bromide SCHEMBL28616524 0.76 CA12 (0.50) TSHRHSD17B10ALDH1A1CYP3A4CA12
SCHEMBL34461940 0.76 CA12 (0.50) TSHRHSD17B10ALDH1A1CYP3A4CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118465140-B Rapid detection method for aromatic nitrogen-containing disinfection byproducts in biological tissues 同济大学 2024-11-05 CN disclosed
CN-118465140-A Rapid detection method for aromatic nitrogen-containing disinfection byproducts in biological tissues 同济大学 2024-08-09 CN disclosed