Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1400054 | 1.00 | KDM4E (0.53) | KDM4EGLAAPEX1TDP1MYC | |
| SCHEMBL11785271 | 0.85 | KDM4E (0.50) | KDM4EGLAAPEX1TDP1MYC | |
| SCHEMBL30301887 | 0.85 | KDM4E (0.48) | KDM4EGLAAPEX1TDP1MYC | |
| SCHEMBL2042628 | 0.85 | KDM4E (0.48) | KDM4EGLAAPEX1TDP1MYC | |
| SCHEMBL23243427 | 0.82 | KDM4E (0.55) | KDM4EGLAAPEX1TDP1MYC | |
| SCHEMBL31125276 | 0.82 | KDM4E (0.55) | KDM4EGLAAPEX1TDP1MYC | |
| SCHEMBL3172005 | 0.82 | KDM4E (0.55) | KDM4EGLAAPEX1TDP1MYC | |
| SCHEMBL6844857 | 0.82 | KDM4E (0.55) | KDM4EGLAAPEX1TDP1MYC | |
| SCHEMBL4814721 | 0.81 | APEX1 (0.55) | KDM4EGLAAPEX1TDP1MYC | |
| SCHEMBL4941800 | 0.81 | ALDH1A1 (0.57) | KDM4EGLAAPEX1MYCNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496142-A | Aryl alkylamine compound and preparation method and application thereof | 仁合益康集团有限公司 | 2024-08-16 | — | — | CN | disclosed |