Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | PAK4 | O96013 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20772934 | 1.00 | KMT2A (0.47) | KMT2AMAPTMEN1LMNANPSR1 | |
| SCHEMBL30966523 | 0.87 | MAPT (0.46) | KMT2AMAPTMEN1LMNANPSR1 | |
| SCHEMBL6024765 | 0.87 | MAPT (0.44) | KMT2AMAPTMEN1LMNANPSR1 | |
| SCHEMBL18551961 | 0.86 | ATM (0.46) | KMT2AMEN1LMNAALDH1A1HPGD | |
| SCHEMBL29853167 | 0.85 | EGFR (0.46) | KMT2AMAPTMEN1LMNANPSR1 | |
| SCHEMBL21437928 | 0.85 | EGFR (0.46) | KMT2AMAPTMEN1LMNANPSR1 | |
| SCHEMBL13751380 | 0.85 | HPGD (0.45) | KMT2AMAPTMEN1LMNAALDH1A1 | |
| SCHEMBL12069886 | 0.84 | MAPT (0.44) | KMT2AMAPTMEN1LMNANPSR1 | |
| SCHEMBL30336943 | 0.84 | ALDH1A1 (0.45) | KMT2AMAPTMEN1LMNANPSR1 | |
| SCHEMBL1680849 | 0.84 | ALDH1A1 (0.45) | KMT2AMAPTMEN1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496142-A | Aryl alkylamine compound and preparation method and application thereof | 仁合益康集团有限公司 | 2024-08-16 | — | — | CN | disclosed |