Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ME3 | Q16798 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25042072 | 0.85 | HRH3 (0.47) | MAPTKDM4EL3MBTL3L3MBTL1CYP3A4 | |
| SCHEMBL31053585 | 0.83 | MAPT (0.42) | MAPTKDM4EL3MBTL3L3MBTL1CYP3A4 | |
| SCHEMBL25042402 | 0.81 | L3MBTL3 (0.40) | MAPTL3MBTL3L3MBTL1CYP3A4SMN1; SMN2 | |
| SCHEMBL25039440 | 0.81 | SMN1; SMN2 (0.40) | MAPTKDM4EL3MBTL3L3MBTL1CYP3A4 | |
| SCHEMBL25041356 | 0.80 | MAPT (0.40) | MAPTKDM4EL3MBTL3L3MBTL1CYP3A4 | |
| SCHEMBL25041476 | 0.80 | SMN1; SMN2 (0.43) | MAPTKDM4EL3MBTL1SMN1; SMN2MGLL | |
| SCHEMBL25041477 | 0.78 | SMN1; SMN2 (0.42) | MAPTKDM4EL3MBTL1SMN1; SMN2MGLL | |
| SCHEMBL15189523 | 0.77 | ADRB1 (0.48) | MAPTL3MBTL3L3MBTL1CYP3A4MGLL | |
| SCHEMBL30885146 | 0.77 | L3MBTL3 (0.40) | MAPTKDM4EL3MBTL3L3MBTL1CYP3A4 | |
| SCHEMBL10035931 | 0.77 | MAPT (0.53) | MAPTKDM4EL3MBTL3L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151252-B | Iron death inhibitor-diarylamine acetamides | 维泰瑞隆有限公司 | 2024-08-27 | — | — | CN | disclosed |