Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25027146 | 0.77 | HSD11B1 (0.38) | SMN1; SMN2KMT2AKDM4EMEN1TSHR | |
| SCHEMBL31597106 | 0.77 | HSD11B1 (0.38) | SMN1; SMN2KMT2AKDM4EMEN1TSHR | |
| SCHEMBL25027295 | 0.76 | HSD11B1 (0.38) | SMN1; SMN2KMT2AKDM4EMEN1TSHR | |
| SCHEMBL11874548 | 0.73 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2LMNAL3MBTL1KMT2A | |
| SCHEMBL25027149 | 0.73 | ALDH1A1 (0.42) | ALDH1A1LMNAL3MBTL1KMT2AKDM4E | |
| SCHEMBL24119880 | 0.73 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL8407103 | 0.72 | GAA (0.59) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL30137493 | 0.70 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2LMNAL3MBTL1KMT2A | |
| SCHEMBL30137406 | 0.70 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL12518235 | 0.69 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118475567-A | Heterocyclic derivative, composition and pharmaceutical application thereof | 西藏海思科制药有限公司 | 2024-08-09 | — | — | CN | disclosed |