SCHEMBL3105394

SCHEMBL3105394

CC(C)(C)c1ccccc1OCC1CCN(C(=O)C(=O)O)CC1

nearest known ligand 0.70

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RBP4 P02753 12/20 0.70
KDM4E B2RXH2 2/20 0.51
ALDH1A1 P00352 2/20 0.51
GAA P10253 2/20 0.48
MEN1 O00255 1/20 0.48
MAPT P10636 1/20 0.48
KMT2A Q03164 1/20 0.48
DPP4 P27487 1/20 0.48
HTR7 P34969 1/20 0.46
TTR P02766 2/20 0.45
RXRA P19793 1/20 0.45
RXRB P28702 1/20 0.45
RXRG P48443 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3099086 0.93 RBP4 (0.78) RBP4KDM4EALDH1A1GAAMEN1
SCHEMBL13299624 0.90 RBP4 (0.64) RBP4KDM4EALDH1A1GAAMEN1
SCHEMBL13034496 0.89 RBP4 (0.69) RBP4DPP4HTR7TTR
SCHEMBL3094531 0.89 RBP4 (0.59) RBP4KDM4EALDH1A1GAAMEN1
SCHEMBL18404066 0.89 RBP4 (0.68) RBP4KDM4EALDH1A1GAAMEN1
SCHEMBL3100388 0.87 RBP4 (0.70) RBP4KDM4EALDH1A1GAAMEN1
SCHEMBL3096133 0.87 RBP4 (0.87) RBP4KDM4EALDH1A1GAAMEN1
SCHEMBL3105936 0.86 RBP4 (0.66) RBP4DPP4HTR7TTR
SCHEMBL3105924 0.86 RBP4 (0.62) RBP4GAAMEN1MAPTKMT2A
SCHEMBL3096298 0.86 RBP4 (0.72) RBP4TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250241902-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION BELITE BIO INC (US) 2025-07-31 US claimed
CN-120129485-A Methods, compositions, and systems for assessing visual function 英属开曼群岛商倍亮生物有限公司 2025-06-10 CN claimed
US-20240248099-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION BELITE BIO, LLC 2024-07-25 US claimed
EP-4340701-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION Belite Bio, LLC (US) 2024-03-27 EP claimed
CN-117440774-A Biomarkers of age-related macular degeneration 倍亮生物有限责任公司 2024-01-23 CN claimed
WO-2022246238-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION BELITE BIO, LLC (US) 2022-11-24 WO claimed
US-9487509-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-11-08 US claimed
US-20140066420-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2014-03-06 US claimed
US-20250241902-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION BELITE BIO INC (US) 2025-07-31 US disclosed
CN-120129485-A Methods, compositions, and systems for assessing visual function 英属开曼群岛商倍亮生物有限公司 2025-06-10 CN disclosed
EP-4507566-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION Belite Bio, Inc (US) 2025-02-19 EP disclosed
US-20240248099-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION BELITE BIO, LLC 2024-07-25 US disclosed
EP-4340701-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION Belite Bio, LLC (US) 2024-03-27 EP disclosed
CN-117440774-A Biomarkers of age-related macular degeneration 倍亮生物有限责任公司 2024-01-23 CN disclosed
US-8586571-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2013-11-19 US disclosed
US-8586571-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2013-11-19 US disclosed
US-20100292206-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-11-18 US disclosed
US-20100292206-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-11-18 US disclosed
US-20100292206-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-11-18 US disclosed
EP-2202223-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2010-06-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250241902-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION PDE6C, SERPINA6, PDE6H RBP4 11/4885KDM4E 4721/4885ALDH1A1 1432/4885
US-20240248099-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION AGER, RBP4, RBP1 RBP4 2/4885KDM4E 4694/4885ALDH1A1 978/4885
US-20140066420-A1 HETEROCYCLIC COMPOUND RBP4, RBP1, RAVER1 RBP4 1/4885KDM4E 334/4885ALDH1A1 933/4885
US-20100292206-A1 HETEROCYCLIC COMPOUND RBP4, RBP1, RAVER1 RBP4 1/4885KDM4E 334/4885ALDH1A1 933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.