Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 3/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.39 |
| ▸ | WDR91 | A4D1P6 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22012060 | 0.98 | CA2 (0.43) | CA2F10PARP1PARP2WDR91 | |
| SCHEMBL31054256 | 0.88 | CA2 (0.42) | CA2F10PARP1PARP2MAOA | |
| SCHEMBL30244447 | 0.87 | PARP1 (0.38) | F10PARP1PARP2WDR91MAOA | |
| SCHEMBL22012059 | 0.83 | F10 (0.41) | F10PARP1PARP2WDR91MAOA | |
| SCHEMBL10648892 | 0.78 | NOTUM (0.44) | CA2ALDH1A1KMT2A | |
| SCHEMBL10649011 | 0.77 | DRD2 (0.40) | CA2DRD2 | |
| SCHEMBL10661686 | 0.77 | HDAC6 (0.40) | CA2 | |
| SCHEMBL22012058 | 0.73 | DRD2 (0.36) | F10PARP1PARP2WDR91DRD2 | |
| SCHEMBL29505746 | 0.72 | CA2 (0.54) | CA2ALDH1A1MAPTMEN1HPGD | |
| SCHEMBL29401046 | 0.72 | CA2 (0.54) | CA2ALDH1A1MEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118475558-A | Sulfonylurea compound | 瑞石生物医药有限公司 | 2024-08-09 | — | — | CN | disclosed |