SCHEMBL31054476

SCHEMBL31054476

Nc1cnc2nccnn12

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MET P08581 1/20 0.32
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
HSP90AA1 P07900 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16419894 0.68 DGAT1 (0.31)
SCHEMBL2650531 0.67 ALDH1A1 (0.46) ALDH1A1GAA
SCHEMBL1650004 0.67 ALDH1A1 (0.49) ALDH1A1POLBGAA
SCHEMBL2392859 0.65 MKNK1 (0.53) ALDH1A1
Iodide SCHEMBL30293374 0.65 ALDH1A1 (0.47) ALDH1A1POLBGAA
Hydrochloric Acid SCHEMBL31049672 0.65 ALDH1A1 (0.47) ALDH1A1POLBGAA
SCHEMBL14034371 0.62 HSD17B10 (0.38) METALDH1A1POLB
SCHEMBL5045194 0.58
SCHEMBL30537 0.55 DGAT1 (0.42) ALDH1A1POLBGAA
SCHEMBL4067471 0.54

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4665454-A1 IMIDAZOTRIAZINE IL-17A MODULATORS AND USES THEREOF Dice Alpha, Inc. (US) 2025-12-24 EP disclosed
WO-2024173173-A1 IMIDAZOTRIAZINE IL-17A MODULATORS AND USES THEREOF DICE ALPHA, INC. (US) 2024-08-22 WO disclosed