Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 15/20 | 0.84 |
| ▸ | MEN1 | O00255 | 4/20 | 0.84 |
| ▸ | NPC1 | O15118 | 4/20 | 0.84 |
| ▸ | RAB9A | P51151 | 4/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.72 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.69 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31243 | 0.91 | SCD (1.00) | SCDMEN1NPC1RAB9AKMT2A | |
| SCHEMBL16554101 | 0.89 | HTT (0.71) | SCDMEN1NPC1RAB9AKMT2A | |
| SCHEMBL31024 | 0.88 | HSD17B1 (0.82) | SCDMEN1NPC1RAB9AKMT2A | |
| SCHEMBL2483241 | 0.88 | SCD (0.84) | SCDMEN1NPC1RAB9AKMT2A | |
| SCHEMBL2753553 | 0.88 | SCD (0.93) | SCDMEN1NPC1RAB9AKMT2A | |
| SCHEMBL4917956 | 0.87 | SCD (0.82) | SCDMEN1NPC1RAB9AKMT2A | |
| SCHEMBL22130146 | 0.87 | SCD (0.87) | SCDMEN1NPC1RAB9AKMT2A | |
| SCHEMBL31219331 | 0.87 | SCD (0.87) | SCDMEN1NPC1RAB9AKMT2A | |
| SCHEMBL13329360 | 0.86 | HSD17B1 (0.74) | SCDMEN1NPC1RAB9AKMT2A | |
| SCHEMBL16562121 | 0.86 | SCD (0.89) | SCDMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609089-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2013-07-03 | — | — | EP | claimed |
| WO-2012025638-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2012-03-01 | — | — | WO | claimed |
| EP-2609089-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2013-07-03 | — | — | EP | disclosed |
| WO-2012025638-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012025638-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2012-03-01 | — | — | WO | disclosed |