SCHEMBL31055029

SCHEMBL31055029

O=C(Cn1cc(Cl)cn1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
TDP1 Q9NUW8 1/20 0.56
HSD17B10 Q99714 1/20 0.55
ALDH1A1 P00352 4/20 0.48
KDM4E B2RXH2 2/20 0.48
LMNA P02545 2/20 0.47
PKM P14618 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
RAB9A P51151 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
SRC P12931 2/20 0.45
ALPI P09923 1/20 0.43
ALPG P10696 1/20 0.43
PLAA Q9Y263 1/20 0.43
KMT2A Q03164 3/20 0.43
GAA P10253 1/20 0.43
MEN1 O00255 1/20 0.43
MAPT P10636 1/20 0.43
NPC1 O15118 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5697676 0.89 HSD17B10 (0.56) POLBL3MBTL1TDP1HSD17B10ALDH1A1
SCHEMBL9373442 0.84 F2 (0.57) POLBL3MBTL1TDP1HSD17B10ALDH1A1
SCHEMBL31054978 0.81 KMT2A (0.48) POLBALDH1A1KDM4ELMNAPKM
SCHEMBL31055021 0.81 SRC (0.45) POLBL3MBTL1TDP1ALDH1A1KDM4E
SCHEMBL8986686 0.81 SRC (0.45) POLBTDP1KDM4ERAB9ASMN1; SMN2
SCHEMBL960168 0.79 HSD17B10 (0.56) POLBL3MBTL1TDP1HSD17B10ALDH1A1
SCHEMBL4130206 0.78 HSD17B10 (0.52) POLBL3MBTL1TDP1HSD17B10ALDH1A1
SCHEMBL8986697 0.78 ALDH1A1 (0.51) L3MBTL1HSD17B10ALDH1A1KDM4ERAB9A
SCHEMBL5138924 0.77 POLB (0.45) POLBLMNASRCALPIALPG
SCHEMBL27609084 0.76 ALPI (0.43) POLBTDP1ALDH1A1KDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118726999-A Preparation method of phosphoryl azole acetophenone derivatives 上海兆维科技发展有限公司 2024-10-01 CN disclosed