SCHEMBL5138924

SCHEMBL5138924

N#Cc1cnn(CC(=O)c2ccccc2)c1

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.45
HSD11B1 P28845 2/20 0.43
SRC P12931 1/20 0.42
LMNA P02545 1/20 0.42
ALPI P09923 1/20 0.41
ALPG P10696 1/20 0.41
PLAA Q9Y263 1/20 0.41
EP300 Q09472 1/20 0.40
FNTA P49354 1/20 0.40
FNTB P49356 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4153053 0.86 SMN1; SMN2 (0.46) LMNAALPIALPGPLAA
SCHEMBL8986686 0.77 SRC (0.45) POLBSRCALPIALPGPLAA
SCHEMBL31055021 0.77 SRC (0.45) POLBSRCALPIALPGPLAA
SCHEMBL31055029 0.77 POLB (0.56) POLBSRCLMNAALPIALPG
SCHEMBL31054978 0.77 KMT2A (0.48) POLBSRCLMNAALPIALPG
SCHEMBL24506420 0.76 GABRD (0.40) EP300
SCHEMBL2629800 0.73 L3MBTL1 (0.57)
SCHEMBL27609084 0.72 ALPI (0.43) POLBSRCALPIALPGPLAA
SCHEMBL16108779 0.71 KMT2A (0.46) POLB
SCHEMBL10784441 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7345080-B2 Substituted 4-pyrazolyl pyrazonlines used for pest control BAYER CROPSCIENCE AG (DE) 2008-03-18 US disclosed
CN-100349891-C Substituted 4-pyrazolyl pyrazolines for pest control agents BAYER CROPSCIENCE AG (DE) 2007-11-21 CN disclosed
CN-1646523-A Substituted 4-pyrazolyl pyrazolines for pest control agents BAYER CROPSCIENCE AG (DE) 2005-07-27 CN disclosed
US-20050159603-A1 Substituted 4-pyrazolyl pyrazonlines used for pest control BAYER CROPSCIENCE AG (DE) 2005-07-21 US disclosed
EP-1478644-A1 SUBSTITUTED 4-PYRAZOLYL PYRAZOLINES USED FOR PEST CONTROL Bayer CropScience AG (DE) 2004-11-24 EP disclosed
WO-2003070724-A1 SUBSTITUTED 4-PYRAZOLYL PYRAZOLINES USED FOR PEST CONTROL BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-08-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050159603-A1 Substituted 4-pyrazolyl pyrazonlines used for pest control L3MBTL4, L3MBTL3, PTMS POLB 4747/4885HSD11B1 4551/4885SRC 3552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.