Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25234821 | 1.00 | SCN9A (0.48) | SCN9ASCN5AABCB11CYP2C9SCN1A | |
| SCHEMBL25276617 | 0.81 | PRKAG1 (0.46) | — | |
| SCHEMBL31055692 | 0.81 | PRKAG1 (0.46) | — | |
| SCHEMBL25281510 | 0.76 | CNR1 (0.43) | SCN9A | |
| SCHEMBL1891278 | 0.72 | OPRK1 (0.46) | SCN9A | |
| SCHEMBL16659027 | 0.72 | SCN9A (0.55) | SCN9ASCN5A | |
| SCHEMBL23835458 | 0.70 | GAA (0.41) | — | |
| SCHEMBL30464600 | 0.70 | SOS1 (0.43) | — | |
| SCHEMBL25280246 | 0.70 | SOS1 (0.43) | — | |
| SCHEMBL30464605 | 0.70 | SOS1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118488953-A | Bicyclic heterocyclic compounds useful as monoacylglycerol lipase inhibitors | 豪夫迈·罗氏有限公司 | 2024-08-13 | — | — | CN | disclosed |