Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26975352 | 0.89 | NLRP3 (0.43) | NLRP3GAA | |
| SCHEMBL31055694 | 0.88 | MEN1 (0.39) | NLRP3ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL22460320 | 0.87 | GAA (0.52) | NLRP3MEN1KMT2AGAA | |
| SCHEMBL26975353 | 0.86 | NLRP3 (0.51) | NLRP3 | |
| SCHEMBL31055693 | 0.85 | NLRP3 (0.48) | NLRP3GAA | |
| SCHEMBL31055695 | 0.85 | NLRP3 (0.48) | NLRP3GAA | |
| SCHEMBL31055732 | 0.84 | NLRP3 (0.47) | NLRP3GAA | |
| SCHEMBL31055707 | 0.84 | NLRP3 (0.47) | NLRP3GAA | |
| SCHEMBL20634277 | 0.82 | NLRP3 (0.46) | NLRP3ALDH1A1 | |
| SCHEMBL31055698 | 0.81 | NLRP3 (0.45) | NLRP3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3416948-B1 | INDACENE BEARING SULFONYLUREAS AS ANTI-INFLAMMATORY AGENTS | UNIV QUEENSLAND (AU) | 2024-07-24 | — | — | EP | claimed |