Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26975363 | 0.89 | ACHE (0.44) | NLRP3ACHEGAA | |
| SCHEMBL31055722 | 0.88 | ACHE (0.41) | NLRP3ACHEENPP2GAA | |
| SCHEMBL22460320 | 0.88 | GAA (0.52) | NLRP3GAA | |
| SCHEMBL31055695 | 0.86 | NLRP3 (0.48) | NLRP3GAA | |
| SCHEMBL26975364 | 0.85 | NLRP3 (0.52) | NLRP3 | |
| SCHEMBL31055707 | 0.85 | NLRP3 (0.47) | NLRP3GAA | |
| SCHEMBL31055701 | 0.85 | NLRP3 (0.47) | NLRP3GAA | |
| SCHEMBL31055732 | 0.85 | NLRP3 (0.47) | NLRP3GAA | |
| SCHEMBL31055689 | 0.84 | NLRP3 (0.47) | NLRP3 | |
| SCHEMBL19259633 | 0.82 | NLRP3 (0.45) | NLRP3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3416948-B1 | INDACENE BEARING SULFONYLUREAS AS ANTI-INFLAMMATORY AGENTS | UNIV QUEENSLAND (AU) | 2024-07-24 | — | — | EP | claimed |