Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31160116 | 0.82 | ALDH1A1 (0.43) | SMN1; SMN2HCAR3VCAM1KDM4EMAPT | |
| SCHEMBL27255556 | 0.82 | ALDH1A1 (0.43) | SMN1; SMN2HCAR3VCAM1KDM4EMAPT | |
| SCHEMBL31123060 | 0.81 | NOTUM (0.43) | SMN1; SMN2NOTUMVCAM1KDM4EMAPT | |
| SCHEMBL3646690 | 0.81 | NOTUM (0.43) | SMN1; SMN2NOTUMVCAM1KDM4EMAPT | |
| SCHEMBL22085608 | 0.79 | LMNA (0.54) | SMN1; SMN2KDM4EMAPTPOLBALDH1A1 | |
| SCHEMBL31651636 | 0.78 | HPGD (0.41) | SMN1; SMN2NOTUMVCAM1KDM4EMAPT | |
| SCHEMBL31159767 | 0.78 | SMN1; SMN2 (0.40) | SMN1; SMN2HCAR3NOTUMVCAM1KDM4E | |
| SCHEMBL31160079 | 0.77 | MAPT (0.41) | SMN1; SMN2HCAR3VCAM1KDM4EMAPT | |
| SCHEMBL1966920 | 0.77 | KDM4E (0.50) | SMN1; SMN2HCAR3VCAM1KDM4EMAPT | |
| SCHEMBL29832958 | 0.77 | KDM4E (0.50) | SMN1; SMN2HCAR3VCAM1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |