Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056011 | 1.00 | ERN1 (0.48) | ERN1ABL1CA12CA1CA2 | |
| SCHEMBL31336100 | 0.84 | ERN1 (0.51) | ERN1CA12CA1CA2CA7 | |
| SCHEMBL1161943 | 0.84 | ERN1 (0.51) | ERN1CA12CA1CA2CA7 | |
| SCHEMBL14885169 | 0.82 | CA12 (0.50) | ABL1CA12CA1CA2CA7 | |
| SCHEMBL18309294 | 0.82 | GAA (0.50) | ABL1LMNAGAATSHRMEN1 | |
| SCHEMBL22717494 | 0.81 | ERN1 (0.53) | ERN1CA12CA1CA2CA7 | |
| SCHEMBL2650105 | 0.80 | GAA (0.50) | ABL1CA12CA1CA2CA7 | |
| SCHEMBL31056271 | 0.80 | ERN1 (0.48) | ERN1CA12CA1CA2CA7 | |
| SCHEMBL14032499 | 0.79 | GAA (0.44) | ERN1ABL1LMNAGAATSHR | |
| SCHEMBL17632541 | 0.79 | ALDH1A1 (0.50) | ERN1LMNAGAATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |