Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 6/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1928118 | 0.86 | ABCB11 (0.32) | ABCB11CYP1A2CYP3A4TSHRHTR2A | |
| SCHEMBL1926293 | 0.76 | FBP1 (0.34) | ABCB11CYP1A2CYP3A4TSHRHTR2A | |
| SCHEMBL3103668 | 0.73 | MAPT (0.42) | CYP1A2CYP3A4TSHRMAOBHTT | |
| SCHEMBL3103661 | 0.73 | MAPT (0.37) | CYP1A2CYP3A4HPGDMEN1KMT2A | |
| SCHEMBL29362445 | 0.70 | PARP1 (0.34) | HPGDALDH1A1 | |
| SCHEMBL3103588 | 0.68 | MCL1 (0.38) | CYP3A4TSHRHTTHPGDALDH1A1 | |
| SCHEMBL3646689 | 0.68 | TDP1 (0.38) | CYP1A2TSHRHPGDKMT2AALDH1A1 | |
| SCHEMBL3103586 | 0.68 | MCL1 (0.33) | CYP3A4TSHRHPGDMEN1KMT2A | |
| SCHEMBL1928587 | 0.68 | FBP1 (0.39) | ABCB11CYP1A2CYP3A4TSHRHTR2A | |
| SCHEMBL3103581 | 0.67 | TSHR (0.35) | TSHRHTR2AHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185520-B1 | FUNGICIDAL 2-ALKYLTHIO-2-QUINOLINYLOXY-ACETAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-12-26 | — | — | EP | disclosed |
| US-20100256183-A1 | FUNGICIDAL 2-ALKYLTHIO-2-QUINOLINYLOXY-ACETAMIDE DERIVATIVES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-07 | — | — | US | disclosed |
| EP-2185520-A1 | FUNGICIDAL 2-ALKYLTHIO-2-QUINOLINYLOXY-ACETAMIDE DERIVATIVES | Sygenta Participations AG. (CH) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009030469-A1 | FUNGICIDAL 2-ALKYLTHIO-2-QUINOLINYLOXY-ACETAMIDE DERITVATIVES | SYGENTA PARTICIPATIONS AG, (CH) | 2009-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256183-A1 | FUNGICIDAL 2-ALKYLTHIO-2-QUINOLINYLOXY-ACETAMIDE DERIVATIVES | CYP1A2, AADAC, CYP51A1 | ABCB11 904/4885CYP1A2 1/4885CYP3A4 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.