Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.40 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056268 | 0.89 | ERN1 (0.41) | KDM4EALDH1A1POLBL3MBTL1ERN1 | |
| SCHEMBL31056819 | 0.78 | FOLH1 (0.40) | KDM4EALDH1A1POLBL3MBTL1FOLH1 | |
| SCHEMBL27594451 | 0.77 | CCNB2 (0.46) | KDM4EALDH1A1POLBL3MBTL1PTGER1 | |
| SCHEMBL14454387 | 0.74 | MAOA (0.49) | KDM4EALDH1A1POLBL3MBTL1CCNB2 | |
| SCHEMBL5749968 | 0.71 | NR4A2 (0.54) | PTGER1PTGER4PTGER3PTGER2MEN1 | |
| SCHEMBL9082648 | 0.71 | NR4A2 (0.54) | KDM4EALDH1A1PTGER1CCNB2CDK1 | |
| SCHEMBL31418731 | 0.71 | HNF4A (0.53) | ALDH1A1 | |
| SCHEMBL13220559 | 0.70 | ERN1 (0.46) | L3MBTL1FOLH1MCL1PTGER1ERN1 | |
| SCHEMBL1539204 | 0.70 | SMN1; SMN2 (0.52) | KDM4EALDH1A1POLBL3MBTL1ERN1 | |
| SCHEMBL18893873 | 0.70 | ERN1 (0.52) | L3MBTL1PTGER1ERN1CCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |