Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056135 | 0.91 | MEN1 (0.42) | LMNAHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL31056582 | 0.83 | LMNA (0.56) | LMNAHPGDALDH1A1USP2TSHR | |
| SCHEMBL31055907 | 0.83 | LMNA (0.56) | LMNAHPGDALDH1A1KDM4EUSP2 | |
| SCHEMBL31056523 | 0.81 | HPGD (0.53) | LMNAHPGDALDH1A1KDM4EUSP2 | |
| SCHEMBL31056024 | 0.78 | LMNA (0.50) | LMNAHPGDALDH1A1USP2TSHR | |
| SCHEMBL31056267 | 0.78 | LMNA (0.50) | LMNAHPGDALDH1A1USP2TSHR | |
| SCHEMBL31056108 | 0.78 | HPGD (0.50) | LMNAHPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL31056810 | 0.76 | MEN1 (0.44) | LMNAHPGDSLC6A5MEN1KMT2A | |
| SCHEMBL31056278 | 0.75 | MRGPRX4 (0.47) | LMNAHPGDSLC6A5HSD17B10MEN1 | |
| SCHEMBL31056249 | 0.74 | KMT2A (0.45) | LMNAHPGDALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |