Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | PRKX | P51817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056479 | 0.90 | MEN1 (0.47) | KMT2AKDM4EHPGDFABP4ALDH1A1 | |
| SCHEMBL28857697 | 0.83 | KMT2A (0.60) | KMT2ATDP1SLC6A2SLC6A3KDM4E | |
| SCHEMBL31056336 | 0.78 | KMT2A (0.50) | KMT2ATDP1SLC6A2SLC6A3KDM4E | |
| SCHEMBL31056582 | 0.77 | LMNA (0.56) | KMT2ALMNAHPGDALDH1A1NPC1 | |
| SCHEMBL31055907 | 0.77 | LMNA (0.56) | KMT2AKDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL31055861 | 0.76 | MEN1 (0.47) | KMT2ASLC6A2SLC6A3LMNAHPGD | |
| SCHEMBL3229895 | 0.75 | KDM4E (0.60) | KMT2ATDP1SLC6A2SLC6A3KDM4E | |
| SCHEMBL4241842 | 0.74 | KDM4E (0.62) | KMT2ATDP1SLC6A2SLC6A3KDM4E | |
| SCHEMBL31056523 | 0.74 | HPGD (0.53) | KMT2AKDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL31056278 | 0.74 | MRGPRX4 (0.47) | KMT2ATDP1LMNAHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |