Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11685931 | 0.82 | MAPT (0.68) | HPGDGAAMAPTCCR5MAOB | |
| SCHEMBL16039680 | 0.81 | CCNB2 (0.43) | HPGDGAAMAPTMAOBMAOA | |
| SCHEMBL21596262 | 0.80 | ALDH1A1 (0.55) | HPGDGAAMAPTTHRBLMNA | |
| SCHEMBL4055189 | 0.80 | GAA (0.51) | HPGDGAAMAPTCCR5MAOB | |
| SCHEMBL31056430 | 0.77 | GAA (0.43) | HPGDGAAMAPTCCR5MAOB | |
| SCHEMBL20140076 | 0.76 | SMN1; SMN2 (0.46) | HPGDGAAMAPTCCR5MAOB | |
| SCHEMBL31056274 | 0.75 | ERN1 (0.49) | HPGDGAAMAPTMAOBMAOA | |
| SCHEMBL20139696 | 0.74 | MAOB (0.52) | MAPTMAOBMAOAERN1CCNB2 | |
| SCHEMBL31500322 | 0.73 | MAPT (0.50) | HPGDGAAMAPTMAOBMAOA | |
| SCHEMBL23796751 | 0.72 | MAOB (0.57) | MAOBMAOALMNAERN1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |